Studi Pustaka Aktivitas Antibakteri Ekstrak Buah dan Daun Tin (Ficus carica)
Abstract
ABSTRACT: Fig plant extracts have been shown to have many biological activities, including as an antimicrobial. Infectious disease is a health problem that continues to grow from time to time. Escherichia coli (E. coli), Klebsiella pneumoniae (K. pneumoniae), Pseudomonas aeruginosa (P. aeruginosa), and Staphylococcus aureus (S. aureus) are the main pathogenic bacteria that cause infection. This literature review is intended to determine the antibacterial potential of fig fruit and leaf extracts against these four bacteria and to determine the class of compounds contained in fig fruit and leaf extracts. The study was conducted using the method Systematic Literature Review (SLR) with the keyword "antibacterial Ficus carica MIC". Inhibitory zone diameter and Minimum Inhibitory Concentration (MIC) data from several studies showed fig fruit and leaf extracts had antibacterial activity against E. coli, K. pneumoniae, P. aeruginosa, and S. aureus. Groups of compounds contained in fig fruit extract include flavonoids, tannins, coumarins, alkaloids, phenols, and anthocyanins and the class of compounds contained in fig leaf extracts include quinolone alkaloids, coumarins, and phenols.
Keywords: Ficus carica, Fig fruit, Fig leaves, antibacterial and antibacterial compound
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ABSTRAK: Ekstrak tanaman tin terbukti memiliki banyak aktivitas biologis diantaranya sebagai antimikroba. Penyakit infeksi merupakan masalah kesehatan yang terus berkembang dari waktu ke waktu. Escherichia coli (E. coli), Klebsiella pneumoniae (K. pneumoniae), Pseudomonas aeruginosa (P. aeruginosa), dan Staphylococcus aureus (S. aureus) merupakan bakteri patogen utama penyebab infeksi. Kajian pustaka ini ditujukan untuk mengetahui potensi antibakteri dari ekstrak buah dan daun tin terhadap keempat bakteri tersebut serta mengetahui golongan senyawa yang terkandung di dalam ekstrak buah dan daun tin. Penelitian dilakukan menggunakan metode Systematic Literature Review (SLR) dengan kata kunci “antibacterial Ficus carica MICâ€. Data diameter zona hambat dan Konsentrasi Hambat Minimum (KHM) dari beberapa penelitian menunjukkan ekstrak buah dan daun tin memiliki aktivitas antibakteri terhadap E. coli, K. pneumoniae, P. aeruginosa, dan S. aureus. Golongan senyawa yang terkandung di dalam ekstrak buah tin diantaranya flavonoid, tanin, kumarin, alkaloid, fenol, dan antosianin dan golongan senyawa yang terkandung di dalam ekstrak daun tin diantaranya alkaloid kuinolon, kumarin, dan fenol.
Kata Kunci: Ficus carica, Fig fruit, Fig leaves, antibacterial and antibacterial compound
Keywords
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DOI: http://dx.doi.org/10.29313/.v0i0.30000
