The Relationship between Obesity and Enhancement Blood Sugar Level, Uric Acid, Cholesterol of Bandung Al-Ihsan Hospital in Year 2015-2017
Abstract
Obesity is a condition of increasing amount of body fat and associated with body mass index. Obesity increase leptin levels and one of the indicators that caused hypothalamus damage and leading to insulin resistance. The function of insulin is to suppress the production of blood glucose levels. Obesity also makes the uric acid level to increase by production of xanthine oxidoreductase. Similarly, cholesterol levels are increased due to the hydrolysis process of triglycerides into low density lipoprotein. The purpose of this study was to determine the relationship of obesity with elevated blood glucose, uric acid, and cholesterol at RSUD Al-Ihsan of Bandung. This research was conducted from 2015-2017. The research methode is analitycal observational with cross-sectional design. The sample of research were 20 people with obese and 20 people without obese. All of them observed the level of blood glucose, uric acid, and cholesterol. As for mann-whitney test and t-independent test results, it was shown that the blood glucose level had p=0,174, uric acid level had p=0,065, and cholesterol level had p=0,109 or p>0,05. In conclusion, there is no relationship between obesity with glood glucose level, uric acid level, and cholesterol level.
Keywords
Full Text:
PDF (Bahasa Indonesia)References
Stunkard AJ and Wadden TA. Obesity: Theory and Therapy. Second ed. New York, NY: Raven Press, 1993.
WHO.int [home page on internet]. Amerika : Obesity and Overweight Inc.; 2000-01 [Update juni 2016; diunduh 10 februari 2017] Tersedia dari; http://www.who.int/mediacentre/factsheets/fs311/en/
Depkes. Riset Kesehatan Dasar. Situasi Kesehatan Gizi dan Obesitas.2013
Dorland’s illustrated medical dictionary. Edisi ke 28. Philladelpia; W.B.Shaunders; 2000.Filamin; Hlm.
Corwin, Elizabeth J. Buku Saku Patofisiologi. Edisi ke-1. Jakarta:EGC; 2009
Guyton ,Arthur and hall. Buku ajar fisiologi kedokteran.Edisi ke-9. Jakarta:ECG ; 2007
Iman, S. 2004. Serangan Jantung dan Stroke Hubungannya dengan Lemak & Kolesterol. Jakarta: PT Gramedia Pustaka Utama dan Beydoun, M.A. 2008. Ethnic diff erences in dairy and related nutrient consumption among US adults and their association with obesity, central obesity, and the metabolic syndrome. Am J Clin Nutr., 87(6): 1914-1925
Sudoyo AW, Setiyohadi B, Alwi I, Simadibrata M, Setiati S. Buku Ajar Ilmu Penyakit Dalam Jilid II edisi V. Jakarta: Interna Publishing; 2009.
Soeroso J, Algristian H. Asam urat Jawaban Praktis Atas Pertanyaan yang Real. Edisi ke-1. Jakarta: Gudang Penerbit; 2011
Kanwar G, Kabra R. Serum uric acid level and obesity: an association. International Journal of Healthcare Sciences. 2016;4(1):52–5.
Purwandari H. Hubungan obesitas dengan kadar gula darah pada karyawan di rumah sakit tingkat IV Madiun. Efektor. 2015;1(25):66–72.
Mushtaq R, Mushtaq R, Akram A, Khwaja S, Ahmed S. Study of serum cholesterol level in adult obese population of Karachi, Pakistan. 2014;4:238–43.
Sipayung EZ, Warouw SM, Manoppo JIC. Hubungan obesitas dengan peningkatan asam urat pada remaja di sekolah menengah pertama. 2013.
Putri AFY, Decroli E, Nasrul E. Hubungan derajat obesitas dengan kadar gula darah puasa pada masyarakat di kelurahan batung taba dan kelurahan korong gadang, kota padang. Jur Kes Andalas. 2015;4(3):707–11.
whitney and rolfes understanding nutrition chapter 9 weight management : overweight, obesity and underweight, WaddsWorth Cengage Learning, 2011 : 296
The role of leptin and ghrelin in the regulation of food intake and body weight in human
uric acid secretion from adipose tissue and its increase in obesity, https://www.ncbi.nlm.nih.gov/pubmed/23913681
Rantung AA, Umboh A, Mantik MFJ. Hubungan hiperkolesterolemia dengan obesitas pada siswa smp eben haezar manado. Jurnal e-CliniC (eCl). 2014;2(2).
http;//semelweis.hu/biokimia/files/2014/08 EN_con_LIPOPROTEINLIPASE_2013.pdf
DOI: http://dx.doi.org/10.29313/kedokteran.v0i0.8452
![](/public/site/images/dadiahmadi/1438603103.png)