Potensi Mikroalga Chaetoceros Calcitrans sebagai Antibakteri terhadap Bakteri Propionibacterium Acnes
Abstract
Abstract. Acne can be caused by bacteria, Propionibacterium acnes. Therefore, in this study I conducted research on the potential of Chaetoceros calcitrans to be used as a source of antibacterial for Propionibacterium acnes. The research was conducted by collecting information through a database of online publications. Chaetoceros calcitrans based on literature studies contains fatty acids, fukosantin, and secondary metabolites such as terpenoids, flavonoids, tannins, and steroids, which are known to have antibacterial activity against P. acnes. Therefore, Chaetoceros calcitans has potential as an antibacterial so that it can be used as an antibacterial candidate against P. acnes.
Keywords: Acne, Antibacterial activity, Propionibacterium acnes, Chaetoceros calcitrans.
Abstrak. Jerawat bisa dipicu oleh bakteri, salah satunya yaitu bakteri Propionibacterium acnes. Maka dari itu pada penelitian ini saya melakukan penelitian mengenai potensi Chaetoceros calcitrans dapat dimanfaatkan sebagai sumber antibakteri Propionibacterium acnes. Penelitian dilakukan dengan mengumpulkan informasi melalui basis data (database) publikasi secara daring (online). Chaetoceros calcitrans berdasarkan studi literatur mengandung asam lemak, fukosantin, dan metabolit sekunder seperti terpenoid, flavonoid, tanin, dan steroid, yang telah diketahui memiliki aktivitas antibakteri terhadap P. acnes. Maka dari itu Chaetoceros calcitans memiliki potensi sebagai antibakteri sehingga dapat dijadikan sebagai kandidat antibakteri terhadap P. acnes.
Kata Kunci: Jerawat, Aktivitas Antibakteri, Propionibacterium acnes, Chaetoceros calcitrans.
Keywords
Full Text:
PDFReferences
Adamakis I. D., Lazaridis P. A., Terzopoulou E., Torofias S., Valari M., Kalaitz P., Rousonikolos V., Gkoutzikostas D., Zouboulis A., Zalidis G., Konstantinos S. (2018). Cultivation, Characterization, and Properties of Chlorella Vulgaris Microalgae with Different Lipid Contents and Effect on Fast Pyrolysis Oil Composition. Article in Environmental Science and Pollution Research: Springer-Verlag GmbH Germany, part of Springer Nature 2018, p. 6-13
Abad M. J., Bedoya L. M., Bermejo P. (2011). Marine Compounds and Their Antimicrobial Activities. Science against microbial pathogens: communicating current research and technological advances. 51, 1293-1306.
Afriyanti, R. N. (2015). Akne Vulgaris Pada Remaja. Fakultas Kedokteran Universitas Lampung. Jurnal Majority, Vol.4/No.6.
Amiguet T. V., Linda E. J., Halimasadia M., Manju S., James B. H., Tony D., Marc A., Rochefort G., and John T. A. (2011). Antibacterial Properties of A Glycolipid-Rich Extract and Active Principle From Nunavik Collections of The Macroalgae Fucus Evanescens C. Agardh (Fucaceae). University of British Columbia.
Amri E., Abdi D., Armaini., Djong H.T. (2017). Screening Anti-Acne Potency of Microalgae: Antibacterial and Antioxidant Activity. Der Pharma Chemica, 9(4):28-31.
Aris S., Sinta P., Dewi K. (2020). Uji Aktivitas Antibakteri Ekstrak Mikroalga Laut Chlorella vulgaris Terhadap Bakteri Propionibacterium acne dan Diformulasikan Sebagai Emulgel. Jurnal Kartika Kimia 3(1), 25-32
Azrifitria., Aziz, S., dan Chairul. (2010). Aktivitas Antibakteri Ekstrak Etanolik Daun dan Umbi Crinum asiatucum L. Terhadap Bateri Penyebab Jerawat. Jakarta: Fakultas Kedokteran dan Ilmu Kesehatan UIN Syarif Hidayatullah.
Bahar A. (2007). Chemistry of Natural Products. New Delhi: Department of Pharmaceutical Chemistry Faculty of Science Jamia Hamdard.
Bhatia, Ajay., Maisonneuve., Jean-Francoise., Persing., David H. (2004). United States: National Academies Press
Bontjura S. (2015). Uji Efek Antibakteri Ekstrak Daun Leilem (Clerodendrum Minahassae L.) Terhadap Bakteri Streptococcus Mutans. Pharmacon, 4(4).
Bramono, S. L. S. M. K., & Indriatmi, W. (2015). Ilmu Penyakit Kulit dan Kelamin. Jakarta: Fakultas KedokteranUniversitas Indonesia.
Cardozo K. H. M., Luiza G., Marques, Carvalho V. M., Carignan M. O., Pinto E., Soriano E.M., Colepicolo P. (2011). Analyses of Photoprotective Compounds in Red Algae from The Brazilian Coast. Rev. bras. Farmacogn. vol.21, no.2.
Cavalieri S.J., Rankin I.D., Harbeck R.J., Sautter R.S., McCarter Y.S., Sharp S.E., Ortez J.H., dan Spiegel J.A. (2005). Manual of Antimicrobial Susceptibility Testing. American Society for Microbiology, USA.
Dart, R. K. (1996). Microbiology of The Analytical Chemistry. London: The Royal Society of Chemistry.
Deyab M.A., Abou-Dobara M.I. (2013). Antibacterial Activity of Some Marine Algal Extracts Against Most Nosocomial Bacterial Infections. Egypt. J. Exp. Biol. Bot. 9, 281–286.
Dwidjoseputro, D. 1980. Pengantar Fisiologi Tumbuhan. Jakarta : Gramedia.
Ganiswara, G. S. (1995). Mikrobiologi Pangan I. Jakarta: Gaya Baru
Heo, S.J., Yoon, W.J., Kim, K.N., Ahn, G.N., Kang, S.M., Kang, D.H., Affan, A., Oh C., Jung, W.K. & Jeon, Y.J. (2010). Evaluation of Anti-inflammatory Effect of Fucoxanthin Isolated from Brown Algae in Lipopolysaccharide-stimulated RAW 264.7 Macrophages. Food Chem. Toxicol., 48:2045–2051.
Higaki, S. (2003). Lipase Inhibitors for The Treatment of Acne. J. Mol. Catal. B. 22: 377-384.
Hoeffler U. (1977). Enzymatic and hemolytic Properties of Propionibacterium Acnes and Related Bacteria. J Bacteriol. 6:555-558.
Iglesiasa M. J., Raquel S., Ian P., Emilie G., Priscillia G., Mehiric M., Yuly L., Virginio C., Ignacio G., Saúl R., Claudio J. V., Felipe L., Sara S., Fernando L. O. (2019). NMR Characterization and Evaluation of Antibacterial and Antiobiofilm Activity of Organic Extracts From Stationary Phase Batch Cultures of Five Marine Microalgae (Dunaliella Sp., D. Salina, Chaetoceros Calcitrans, C. Gracilis And Tisochrysis Lutea). Elsevier Ltd: Phytochemistry, 164 (2019) 0031-9422.
Jawetz, E., Melnick, J. L., Adelberg, E. A., 1996, Mikrobiologi Kedokteran, Edisi ke-20, 213, EGC, Penerbit Buku Kedokteran, Jakarta
Karou D., Savadogo A., Canini A., Yameogo S., Montesano C., Simpore J., Traore A. S. (2005). Antibacterial Activity of Alkaloids from Sida Acuta. African Journal of Biotechnology, 4(12), 195-200.
Karpiński T. M., and Artur A. (2019). Fucoxanthin: An Antibacterial Carotenoid. Antioxidants (Basel). 8(8): 239.
Kim S.M., Jung Y., & Kwon O. (2012). A Potential Commercial Source of Fucoxanthin Extracted from the Microalga Phaeodactylum tricornutum a Potential Commercial Source of Fucoxanthin Extracted from the Microalga Phaeodactylum tricornutum. Appl. Biochem. Biotechnol., 166:1843– 1855. doi: 10.10 07/s12010-012-9602-2
Kumar, S.R., Hosokawa, M. & Miyashita, K. (2013). Fucoxanthin: A Marine Carotenoid Exerting Anti-Cancer Effects by Affecting Multiple Mechanisms. Mar. Drugs, 11:5130–5147. doi : 10.3390/md11125130
Liu Z., Sun X., Sun X., Wang S., Xu Y. (2019). Fucoxanthin Isolated From Undaria Pinnatifida Can Interact With Escherichia Coli And Lactobacilli In The Intestine And Inhibit The Growth Of Pathogenic Bacteria. J. Ocean Univ. China. 2019;18:926–932. doi: 10.1007/s11802-019-4019-y.
Maeda, H., Hosokawa, M. & Sashima, T. (2017). Anti-obesity and Anti-diabetic Effects of Fucoxanthin on Diet-induced Obesity Conditions in a Murine Model. Mar. Drugs, 2:897-902 doi: 10.3892/mmr
Ngajow M., Abidjulu J., Kamu V. S. (2013). Pengaruh Antibakteri Ekstrak Kulit Batang Matoa (Pometia Pinnata) Terhadap Bakteri Staphylococcus Aureus Secara In Vitro.
Okunowo O. W., Afolabib L. O., Umunnakwea I. E., Oyedejia A. O., Ilesanmia J. A. (2016). GC-MS Analysis and Antimicrobial Properties of Methanolic Extracts of The Marine Algae Skeletonema Costatum and Chaetoceros Spp. Biokemistri. 28(1). 24-33.
Pyne J. W., dan Meeting B. (1986). Biologically Active Compounds from Microalgal. Journal of Enzyme Microbe Technology. Vol. 8. Butterworth & Co. Published.
Renhoran M., Dedi N., Iriani S., Uju. (2017). Ekstraksi dan Purifikasi Fukosantin dari Sargassum sp. Sebagai Anti-Acne. Jurnal Pengolahan Hasil Perikanan Indonesia. 20(2). 370-379.
Sachlan, M. (1982). Planktonologi. Semarang: Fakultas Peternakan dan Perikanan Universitas Diponegoro.
Seraspe B.E., Bernadeth F. T., Minda J. F., Ida G. P., Milagros R., and Edgar C. A. (2012). Antibacterial Properties Of The Microalgae Chaetoceros Calcitrans. Asian Fisheries Science. 25. 343-356.
Shannon E., Nissreen A.G. (2016). Antibacterial Derivatives of Marine Algae: An Overview of Pharmacological Mechanisms. Mar. Drug. 14(4). doi:10.3390/md14040081.
Verosa L. F., Sudarno., Heru P. (2018). Activity Test of Crude Extract Gracilaria sp. on Propionibacterium acnes Growth Inhibition In Vitro. Universitas Airlangga, Surabaya.
Vilar GN, Filho JFS, Santos LA. (2015). Quality of Life, Self-esteem and psychosocial factors in Adolescents with Acne vulgaris. Anais Brasileiros de Dermatologia. 2015;90(5):622-9.
Vina J.A., Fajar A.M., Aris S. (2019). Aktivitas Antibakteri dari Mikroalga Laut Porphyridium cruentum terhadap Bakteri Staphylococcus epidermidis dan Propionibacterium acne. Jurnal Agrotek. vol.6 no.2, 63-68
Walailuck B., Yuwadee P., Duangta K., Jeeraporn P., Doungporn A., Chayakorn P., Prasan S., And Panmuk V. (2011). Antimicrobial and Anti-inflammatory Properties of Various Seaweeds from the Gulf of Thailand. International Journal Of Agriculture & Biology. Vol. 13, No. 1, 2011p. 100–104
DOI: http://dx.doi.org/10.29313/.v6i2.24598
