Correlation Between Body Mass Index and Histopathological Finding On Breast Cancer Patient In RS. AL-Islam Bandung

Andini Shellawaty Nugraha, Ismet M. Nur, Siti Annisa Devi Trusda

Abstract


Breast carcinoma is the second most common cancer among women in Indonesia. Body mass index can affect estrogen hormone levels in women, in directly proportional manner. Histopathological examination still become a gold standard for cancer diagnosis and prognostic determination. This study was aimed to determine the relationship of body mass index with histopathological findings. Method used was observational analytic with cross sectional approach. Data was taken from medical record in the form of histopathology examination result of breast carcinoma patient at Al-Islam Hospital Bandung period 2013-2016. Result showed  84 respondents has body mass index group in the normal category (39.3%), most histopathological type of breast cancer was Invasive Ductal Carcinoma (96.3%).  Statistical analysis using chi square test showed that there was a significant relationship between body mass index and histopathology type with p = 0,050 (p≤0,05). Conclusions: there wass a significant relationship between body mass index with histopathological findings in patients with breast carcinoma in RS. Al-Islam Bandung period 2013-2016.


Keywords


body mass index, breast carcinoma, histopathology type

References


American Cancer Society, Society AC. Breast cancer facts & figures. Am Cancer Soc. 2010;8(2):1-34. doi:10.3322/caac.21166.

Kementerian Kesehatan Republik Indonesia. Panduan penatalaksanaan hemofilia. Acuan Pedoman Prakt Klin Kanker Payudara. 2015

Aprianda R, Istiqomah. Situasi Penyakit Kanker. 2015;1–7. Tersedia di: http://www.depkes.go.id/download.php?file=download/pusdatin/buletin/buletinkanker.pdf

Kumar V, Abbas AK, Aster JC. Robbins and Cotran Pathologic Basis of Disease Edisi ke-7. Jakarta: EGC;2007.

Sihombing M, Saparudin AN. Faktor Risiko Tumor Payudara Pada Perempuan Umur 25-65 Tahun di Lima Kelurahan kecamatan Bogor Tengah. Pus Teknol Kesehat dan Epidemiol Klin Badan Penelit dan Pengembangan, Kementeri Kesehat RI. 2014;1(Faktor Risiko Tumor Payudara Pada Perempuan Umur 25-65 Tahun di Lima Kelurahan kecamatan Bogor Tengah):10.

WHO (World Health Organization). Global Data Base On Body Mass Index.Tersediadi:http://apps.who.int/bmi/index.jsp?introPage=intro_3.html

Lee K-H, Keam B, Im S-A, et al. Body mass index is not associated with treatment outcomes of breast cancer patients receiving neoadjuvant chemotherapy: korean data. J Breast Cancer. 2012;15(4):427-433. doi:10.4048/jbc.2012.15.4.427

Hilbertina N. Peranan patologi dalam diagnostik tumor payudara. 2015;38:1-8

Sulistiowati E, Haryono S. Kadar C-Erbb2 Dalam Serum Dan Saliva Pasien Kanker Payudara. Bul Penelit Kesehat. 2014;42(4):223-230. Tesediadi:http://ejournal.litbang.depkes.go.id/index.php/BPK/article/view/3660

Lini Nur Amalia. Hubungan Obesitas dengan Kejadian Kanker Payudara di RSUD Kota Semarang Tahun 2015. Tersedia di: http://perpusnwu.web.id/karyailmiah/documents/4729.pdf

Kurniawati. Pengaruh Penggunaan KB Suntik 3 Bulan Terhadap Peningkatan Indeks Masa Tubuh Pada Akseptor KB Di Desa Kepuh Kembang Kecamatan Peterongan Kabupaten Jombang. Jurnal Edu Health Vol 5 No.1, April 2015.

Aisha Rahmatya. Hubungan Usia dengan Gambaran Klinikopatologi Kanker Payudara di Bagian Bedah RSUP DR. M. Djamil Padang tahun 2015.

Kallionemi, A. Kallionemi, W. Kurisu et al., ERBB2 amplification in breast cancer analyzed by fluorescence in situ hybridization.

Rosai J.2004. Breast, In Rosai and Ackerman’s Surgical Pathology, 9th ed. Philadelphia

Breastcancer.org. IDC — Invasive Ductal Carcinoma [Internet]. 2015. Tersedia di: http://www.breastcancer.org/symptoms/types/idc

Bertrand K A, Tamimi R M, Scott C G, Jensen M R, Pankratz V S,

Vissher D,Norman A. Mammographic density and risk of breast cancer by age and tumor characteristics. Res. 2013:15: R104:1186

Irwan, Hafni Bachtiar, dkk. Perbandingan rognosis Subtipe Molekule Kanker Payudara antara Pasien Kanker Payudara Wanita Usia Muda dan Tua di RSUP DR.M. Djamil Padang tahun 2012-2014. (diunduh: 3 Desember 2015). Tersedia di: file:///C:/Users/andini/Downloads/323-666-1-SM%20(1).pdf




Flag Counter